Enabling precision conservation of threatened species through national-scale genomics infrastructure

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There is a global biodiversity crisis with Australia having the highest mammal extinction rate in the world. Many threatened species now persist only in small, fragmented wild populations or captivity, where loss of genetic diversity further increases extinction risk.

Despite advances in conservation genetics, uptake has historically been limited by fragmented datasets, inconsistent methodologies, and constrained analytical capacity among end-users, reducing the ability of genomic information to directly inform on-ground management decisions.

To address this challenge, the Threatened Species Initiative (TSI), enabled through NCRIS via Bioplatforms Australia, has leveraged national-scale genomics infrastructure including high-throughput sequencing platforms, standardised analytical workflows, integrated data management systems and a custom-built training program to empower conservation managers to apply cutting-edge genomics to threatened species management.

Bilby. Image credit: Yuanyuan Cheng

Since 2020, the Initiative has delivered high-quality, accessible genomic resources for more than 130 threatened species, including the greater bilby, numbat, orange-bellied parrot, and Australia’s two extinct-in-the-wild species (Christmas Island blue-tailed skink; Lister’s gecko).

Genomic data is now being rapidly translated into actionable conservation actions, including optimising breeding programs, identifying genetic rescue opportunities, and designing population reinforcement strategies.

This NCRIS-enabled genomic data infrastructure is delivering transformational change in conservation practice, moving from fragmented, reactive management to predictive, data-driven recovery planning at national scale, improving long-term outcomes for Australia’s most threatened species.

Threatened Species Initiative: Empowering conservation action using genomic resources
https://www.pnas.org/doi/10.1073/pnas.2115643118

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