Bioplatforms Australia drives cancer cures across the nation
Australia is a global leader in cancer genomics research and translation, driving improved survival rates in children and adults. Bioplatforms Australia provides national genomics and bioinformatics infrastructure supporting collaborative programs that convert genomic data into actionable clinical insights across melanoma, paediatric and adult cancers, including the following national initiatives: The Australian Melanoma Genome Project, co-led […]
Australia welcomes its first EMBL ARISE Fellow at Monash University
Australia’s capabilities in research infrastructure (RI) have received a major boost, with Monash University set to host EMBL Fellows as part of the Career Accelerator for Research Infrastructure Scientists (ARISE) – a flagship European initiative designed to train the next generation of RI leaders. ARISE Fellow Dr Richard Jacoby from the European Molecular Biology Laboratory (EMBL) will […]
Bioplatforms Initiative recognised as an official project supporting Australia’s Animal Plan
We are pleased to share that the Bioplatforms Animal Disease Genomics Initiative is now listed as an official project supporting the ambitions of the DAFF Animalplan 2022–2027, Australia’s first national action plan for production animal health. Led by the Department of Agriculture, Fisheries and Forestry (DAFF), Animalplan 2022–2027 provides a coordinated national framework to strengthen […]
Improving spatial analysis for disease risk detection: a COVID-19 case study
During COVID-19, public health agencies relied heavily on data to understand where the virus was spreading and who was most at risk. While robust data have long underpinned decision-making, the pandemic reinforced that statistical factors – such as how data are grouped, how geographical boundaries are defined, and how granular the data are – can […]
Urban greening for health
On average, someone is hospitalised for a heart attack every 9 minutes, according to the National Heart Foundation of Australia. And the toll on taxpayers runs into billions each year. Reduced cardiovascular disease Few studies have explored whether health benefits from urban greening translate into reduced healthcare expenditure. Study co-lead Professor Xiaoqi Feng from the University […]
Research impact: understanding bikeability to shape healthier, more connected cities.
Across Australia, cities are looking for safer, easier ways to support cycling. ‘Bikeability’ describes how well an area supports cycling through its infrastructure, safety, environment and access to everyday destinations. But understanding what actually makes an area ‘bikeable’ is not straightforward. Until now, studies have used different definitions, indicators, and modelling approaches to explore bikeability, […]
Strengthening international research relations and showcasing Australian capability
Driving global collaboration through the Prato 2025 Health Research Infrastructure Symposium The 2025 Australian & European Health Research Infrastructure Symposium, held from 16-18 September at the Monash University Prato Centre in Italy, united leaders from major Australian and European research infrastructures to strengthen international partnerships and tackle shared challenges in health and life sciences. The three-day […]
Lab-grown ‘tiny hearts’: development of an epicardial lineage tracing human pluripotent stem cell line to identify new cardiac therapeutics
Lab-grown ‘tiny hearts’ – developed with the support of the Phenomics Australia iPSC Derivation & Gene Editing Facility Node at Murdoch Children Research Institute (MCRI) and the Pipeline Accelerator scheme – have accelerated the way treatments are identified and tested for heart related disease. Cardiovascular disease is a major cause of death in Australia, responsible for one in four of […]
Advancing early melanoma detection: Phenomics Australia & ACEMID collaboration
Phenomics Australia’s Histopathology & Slide Scanning Node is working with the Australian Centre of Excellence in Melanoma Imaging & Diagnosis (ACEMID) Pathology team to drive new advances in the early detection and diagnosis of melanoma. Every year, more than 18,000 Australians are diagnosed with melanoma. According to ACEMID Project Leader Professor H. Peter Soyer (The University of Queensland), identifying […]
Cost-effective imaging technology to revolutionise spatial transcriptomics
EMBL Australia group leader Dr William Roman & his team have launched a new imaging-based spatial transcriptomics platform that dramatically reduces experimental costs from more than $35,000 to approximately $30 per experiment, making spatial biology more accessible to researchers across Australia. While modern sequencing technology has made it relatively easy to tell which genes are […]
Safer and more accurate scans for pregnant women and children
The NIF-supported Australian National Total Body PET Facility creates benefits for both research translation and patient care. Challenge Exposure to ionising radiation is a significant concern for vulnerable patients – particularly pregnant women and children – who may require PET/CT scans for diagnosing or staging cancer, infection, or inflammatory diseases. Traditional methods of reducing radiation […]
NIF helped provide the evidence that led to the approval of Australia’s first dementia treatment
MRI and PET imaging provided essential evidence that supported the approval of donanemab. Challenge Dementia is a major health challenge in Australia, currently affecting nearly half a million people and ranking as the nation’s second-leading cause of death. This number is expected to double by 2058. Donanemab is a new disease-modifying therapy that uses monoclonal […]
NCRIS supports breakthrough ovarian cancer agent from early-stage design to first in-human studies
Australian capabilities shepherded new agent through entire innovation pipeline. Challenge Professor John Hooper has worked for decades to develop antibody 10D7, a beacon of hope for patients with advanced ovarian, prostate and bladder cancers. Very few novel drugs are developed entirely in Australia, from their early stages through to preclinical models and first-in-human trials. Ovarian […]
NIF Node Director leads WHO resolution to improve global imaging access
Increasing imaging capacity will reduce the rising burden of premature deaths from cancer and other diseases. Challenge Each year, about 17 million people die prematurely from cancer and other non-communicable diseases – and this burden is increasing. Imaging plays a critical role in early cancer detection and more effective treatments. Better access to imaging will […]
World’s largest longitudinal muscle MRI study set to benefit children with cerebral palsy
The completed MUGgLE study has produced vital data on muscle growth patterns and muscle under-development in children with cerebral palsy. Challenge Cerebral palsy, the most common physical disability in children, affects ~34,000 Australians. It impacts movement and posture, often leading to muscle weakness and stiffening. Previous studies have typically only examined muscle groups collectively – […]
MAB: advancing bioimaging through collaboration and innovation
EMBL Australia Group Leader Dr Senthil Arumugam, along with Dr Toby Bell and Dr Kate McArthur, recently launched the Monash BDI Advanced Bioimaging (MAB) platform – a researcher-led, global collaboration hub designed to bring innovative microscopy technologies directly to the researchers who need them. From light-sheet imaging to custom-built microscopes and large-scale data visualisation, MAB integrates experimental […]
Research Impact: Geospatial Factors Applied to Road Accidents
Road accidents are a major source of trauma worldwide. Over 1.3 million people are killed in road accidents annually, and collisions are a leading cause of death and injury across all age groups. Aside from the human cost of road accidents, there is a significant financial toll. The US Centre for Disease Control and Prevention […]
TRI boosts medical research efficiency with FileSender
The Translational Research Institute’s integration of FileSender enables fast and secure data sharing, streamlining collaboration for vital medical research. The Translational Research Institute (TRI) is at the forefront of medical research, supporting diverse research projects that produce crucial data to further our understanding of complex diseases. The institute plays a key role in studies spanning cancer biology, […]
Research Impact: Measuring the Age-Friendliness of Australian Suburbs
Australians are ageing at an unprecedented rate. As people get older, frailty and increased use of health resources pose a significant challenge to already strained health services. It is vital to keep ageing populations healthy to not only reduce this dependence on services but also to promote their wellbeing, independence, and participation in society. This […]
Powerful software reveals brain superhighway ‘tracts’ for surgery and research
Our brains work a bit like highly advanced supercomputers, with bundles of white matter, known as ‘tracts,’ acting as superhighways that facilitate information flow and enable various brain functions. Injuries and disturbances in these tracts are linked to numerous neurological and psychiatric disorders. However, imaging these white matter tracts is challenging. These tracts are made […]
Research Impact: Mitigating Childhood Asthma Risks from Traffic-Related Air Pollution
Using data available through AURIN, as well as Westgate and EPA (Environment Protection Authority Victoria) monitor data, researchers from the University of Queensland and the University of Melbourne have raised concerns about the impact of emissions from truck traffic on childhood asthma rates in Melbourne’s Inner West. Clare Walter, Peter D Sly, Brian W Head, […]
Streamlining remote sensing data transfers for environmental research
FileSender addresses the challenge of moving large datasets around for researchers participating in the Joint Remote Sensing Research Program. For environmental researchers, the volume of data generated by remote sensing technologies can be massive and challenging to manage. The Joint Remote Sensing Research Program (JRSRP) is a leader in this field, involving experts from academia […]
Making visible the impact of Australia’s national microscopy infrastructure
Through trust and identity, the impact of Australia’s distributed microscopy infrastructure will be revealed. Microscopy Australia is a consortium of university-based microscopy facilities that provides more than 3,500 Australian researchers a year, with access to state-of the-art microscopes. Through access to their facilities, crucial research is enabled in areas such as future energy innovations, improved […]
New brain imaging set to improve and speed epilepsy diagnosis, treatment
Novel imaging methods combined with cognitive, genetic and medical data will use AI to increase the speed and accuracy of diagnoses and treatment for epilepsy patients, according to researchers working collaboratively with NIF. Advanced MRI imaging methods are helping Australian epilepsy researchers move closer to faster, more accurate, individualised diagnoses and treatment options for patients. […]
Data Without Borders: the role of Globus in international genome research
Genetics technical specialists at the Biomolecular Resource Facility are using the Globus data movement service through AARNet to share huge datasets with national and international collaborators. The Biomolecular Resource Facility (BRF) is located in Canberra within the John Curtin School of Medical Research at the Australian National University (ANU). As a core laboratory providing research […]
Future-proofing computational proteomics
EMBL Australia and Bioplatforms Australia joined forces to host a pivotal proteomics workshop titled ‘Future-proofing Computational Proteomics’ on 24 April, featuring leading guest speakers, Dr Rolf Apweiler, Prof Marc Wilkins and Dr Richard Lipscombe. The Australian proteomics community discussed advancements in proteomics research and the pivotal role of computational approaches in shaping the future of […]
Australian health research infrastructure underpins world-first brain cancer collaboration
The NCRIS Health Group will support Australian brain cancer research through Brain Cancer Australia’s project to develop an integrated network of research platforms to improve patient outcomes, test new treatments and work toward a cure, with the announcement of a Medical Research Future Fund (MRFF) grant worth just under $6M. The project brings together clinicians, […]
The true value of a pure diamond
Professor Steven Prawer from the School of Physics at the University of Melbourne, wants everybody to have diamonds. To improve their quality of life, of course. He’s not imagining diamond rings or jewellery; he’s envisaging quantum computers and health monitors made of diamond. He wants to harness the same clarity and purity that make diamonds […]
Brain research supercharged by new ‘control panel’ accessible worldwide
The flood of data from brain research worldwide has now been channelled into an easy-to-use, open-access processing tool built to supercharge our understanding of the human brain. Neurodesk – a platform for processing, analysing and sharing massive datasets – has solved critical issues in the search for answers about brain disorders and diseases such as epilepsy, […]
Strengthening our European connections to EMBL and beyond
On a recent visit to EMBL Heidelberg, Ian Smith, Chair of the EMBL Australia Council, spoke about the synergies between EMBL and EMBL Australia, opportunities for collaboration and ideas for exciting future programs. Ian Smith, Chair of the EMBL Australia Council, chatted to EMBL about the synergies between the organisations, opportunities for collaboration, and ideas […]
Breaking the Cycle
Data linkage is helping researchers understand the lifelong impact of child abuse and neglect, and how they entrench intergenerational disadvantage. Every year, 1 in 20 Australian children will be reported to child protection. One in 50 children will be the subject of an investigation by authorities and 1 in 100 will have that report substantiated. […]
Clinical Trial Data Unlocked for Research with New National Platform
Health Data Australia is unlocking clinical trial data for research at a national scale. For the first time in Australia, researchers can find clinical trial data from multiple research institutions and request access to it via a new platform, Health Data Australia. Launching tomorrow at SAHMRI in Adelaide, Health Data Australia allows clinical trialists and data […]
CRISPR/Cas as diagnostics tools
Phenomics Australia NCRIS expertise is used in providing knowledge to look into the commercial and translational potential of CRISPR technology. Phenomics Australia’s long-term support of the In vivo Genome Engineering and Disease Modelling nodes over the years has allowed researchers at the Melbourne Advanced Genome Editing Center (MAGEC) to have a solid understanding of CRISPR/Cas […]
When food kills
Infrastructure and expertise supported by Phenomics Australia and Therapeutic Innovation Australia (TIA)are used in fighting food poisoning toxins. Prof Si Ming Man (right) and Dr Anukriti Mathur (left). Image Lannon Harley/ANU The challenge: Food poisoning is estimated to affect more than 4 million Australians every year – costing the economy $1.25 billion, and in some […]
Making life easier – Prof Joe Shapter’s ORCID story
We recently chatted with Joe Shapter, the Pro-Vice-Chancellor (Research Infrastructure) at the University of Queensland (UQ), to learn more about how his ORCID ID has helped him when applying for grants. Joe shared with AAF how his ORCID record was first registered when he was at Flinders University and it continued to be populated when […]
A One Health approach to Japanese encephalitis
Scientists at CSIRO’s Australian Centre for Disease Preparedness (ACDP) provided diagnostic testing and outbreak response support when a widespread outbreak of Japanese encephalitis occurred in piggeries in southern Queensland, New South Wales, Victoria and South Australia. What is Japanese encephalitis? Japanese encephalitis (JE) virus is a potentially fatal disease that infects about 100,000 people worldwide […]
How data linkage can improve the health of older people
Older people, despite bearing the burden of chronic disease and being more likely to take prescription drugs older people are under-represented in clinical trials. Studying older people When pharmaceutical companies do clinical trials, people over the age of 70 are often excluded. It’s partly ageism, says Professor Leon Flicker, a geriatric medicine specialist at The University of Western Australia. […]
How Australia’s national research infrastructure is responding to COVID-19
Australia’s National Research Infrastructure (NRI) swiftly redeployed to support national and international COVID-19 research. Some examples are listed below. Australian Centre for Disease Preparedness (ACDP), Bioplatforms Australia (BPA), Microscopy Australia and Therapautic Innovation Australia (TIA) were involved in the University of Queensland vaccine program. Australian Plant Phenomics Facility (APPF) is supporting research into plant-based vaccines. Astronomy Australia […]
The risk of ‘Mr Fluffy’ insulation
When Australian National University epidemiologist Associate Professor Rosemary Korda first started holding public forums for Canberra residents affected by ‘Mr Fluffy’ insulation, people were very distressed. “There was quite a bit of anger in the room, and pretty upset people,” she remembers. “There were definitely people who were very concerned about future health effects of the […]
Uncovering a rare autoinflammatory disease
Phenomics Australia has enabled an international research consortium to identify the genetic cause of a previously undiagnosed autoinflammatory disease (CRIA Syndrome). The challenge: effective CRIA Syndrome treatment is limited. Humans suffering from this rare condition present a series of painful symptoms of unknown cause, including periodic fevers and swollen lymph nodes, recurring from early childhood […]
New Era in X-Ray Imaging
Next generation X-ray technology, developed and manufactured in Adelaide, is solving global health, defence and security challenges by making X-ray machines significantly lighter and more portable. In-depth imaging is now available on the move thanks to Adelaide-based medical device manufacturer, Micro-X, which has commercialised a new way of producing x-rays. The ASX-listed company is harnessing […]
Developing Personalised Treatment for Kids With Cancer
CAVATICA is a cloud-based platform for collaboratively accessing, sharing, and analysing childhood cancer data. Childhood cancer kills more children than any other disease in Australia and tragically, every week three children and adolescents in Australia currently die because of cancer. Every child is different, every cancer is unique, and so treatment has to be tailored for […]
Tree shade and children’s walking routes – combating skin cancer and obesity in children
Improved modelling of the health and well-being of Australians supports evidence-based health policy and health services planning. Australia has one of the highest rates of skin cancer in the world and school children are amongst the most vulnerable to harmful UV exposure. By contrast, exposure to the sun allows for sufficient vitamin D levels in […]
Elastagen – Skinnovation in treatment for burns victims
Elastagen Pty Ltd is a clinical stage medical device company that is pioneering Elastatherapy™ using the human protein elastin to naturally repair and augment the skin. The company has arisen out of patented research conducted by Prof. Tony Weiss’s group at the University of Sydney and their first clinical trials have demonstrated the biocompatability and […]
Better cholesterol imaging
An international team of researchers has developed a new way to localise cholesterol is in cells and tissues. This provides insights into how cholesterol moves in and out of cells and could eventually lead to new therapies for cardiovascular disease. Deuterated cholesterol enabled by the National Deuteration Facility and NanoSIMS (nano-Secondary Ion Mass Spectroscopy) at […]
Linked Data and the Reduction in Cervical Cancer in Australia
Data linkage has had a significant role in the reduction in cervical cancer in Australia. Preventing cervical cancer The Human Papilloma Virus (HPV) vaccine is a powerful tool for the prevention of cervical cancer. It was developed by industry, based on critical research done at the University of Queensland. Australia was the first country in the world to introduce […]
