About this Provider
Phenomics Australia provides a national capability to explore the human genome and the genetic basis of health and disease. Our openly accessible service delivery centres span twenty locations across Australia. Through these, we offer specialised infrastructure, research services and technical expertise dedicated to advancing our fundamental understanding of health and disease and enabling next-generation innovations in healthcare and therapeutic development to benefit all Australians.
Contact Information
P: +00 0000 000
- The John Curtin School of Medical Research 131 Garran Road, Australian National University Acton ACT 2601, Australia
TYPE OF CLIENTS
Heading of content section
With the advancement of health genomics and precision medicine there exists a significant opportunity for Phenomics Australia to be ambitious in how we develop our support for biomedical researchers and clinicians to discover the genetic drivers of human disease. Leveraging our established strengths, we will continue to deliver new investments in cutting-edge capabilities to address unmet research needs and national health priorities. We will deploy our extensive experience to pursue valuable new collaborations and opportunities for national and international leadership, further enhancing our engagement with academia, healthcare and industry. We will continue to develop our partnerships with prominent and emerging health initiatives and infrastructure providers, to establish integrated development pipelines for research discovery and translation.
HOW WE CAN HELP
Phenomics Australia is at the forefront of facilitating biomedical research through a comprehensive suite of services designed to advance the understanding and treatment of diseases.
Phenomics Australia Biobanking service provides a database and cryobank of mouse sperm and embryos essential for discovering and distributing disease models in Australia.
Phenomics Australia enables genome-scale cell-based CRISPR and compound screening in both 2D and 3D cell lines, PDX, patient-derived cells, and complex disease models using sophisticated liquid handling automation, high content cellular phenotyping, and reporter-based readouts.
Phenomics Australia enables detailed description of the pathological changes in every tissue of in vivo disease models to efficiently determine the biological consequences of genetic mutations and to relate mutant and other disease phenotypes to human disease.
Phenomics Australia supports the production of bespoke in vivo models possessing targeted mutations of interest and which can replicate clinical findings.
To complement our established in vivo capabilities, Phenomics Australia is actively expanding our range of in vitro engineering and disease modelling system to include cell-, organoid- and tissue-based models, as well as 3D bioprinting.
People
Phenomics Australia provides a critical network of scientific and technical leaders and expert personnel to ensure researchers and clinicians have access to training, consultancy, guidance, technical, grant and intellectual support suited to the various needs of the end-users in a supported national hub model.
Biomedical Data Asset
SlideCentre
Australian Phenome Bank (APB)
Missense Mutation Library (MML)
International Mouse Phenotyping Consortium (IMPC)
Services and expertise
3D biology and screening
3D bioprinting
Animal model provision
Arrayed CRISPR screening
Bioinformatics pipeline for quantitative analysis
Compound Screening
Cellular phenotyping
COVID-19 modelling
CRISPR/Cas9 screening
CRISPR/Cas9 technology in mice and cell generation
CROPSeq
Gene targeting in mouse embryonic stem cells
Data provision
Digital slide scanning
DNA construct design and production
Expert analysis and data curation for pathological analysis
Genotyping, phenotyping and associated bioinformatics
Human iPSCs
High-throughput imaging and screening
Mice cryopreservation
Necropsies
Nucleofection
Organoids
Pathological analysis
Patient-derived lines
Pooled viral CRISPR screening
Production of transgenic mice, rats, and other species
Reanimation, redistribution and importation of mice
RNAi screening
Searchable mouse strain databases
shRNA platform
Stem Cell Registry
Tissue scoring
Training, consultancy and technical support
Transgenic Drosophila production
Quality Systems
Our facilities have areas that are compliant with the following quality standards:
ISO17025
ISO9001
OGTR
PC2
SPF
Databases
Our facilities have areas that are compliant with the following quality standards:
